Lamina-specific restoration of serotonergic projections after Nogo-A antibody treatment of spinal cord injury in rats.

@article{Muellner2008LaminaspecificRO,
  title={Lamina-specific restoration of serotonergic projections after Nogo-A antibody treatment of spinal cord injury in rats.},
  author={Angela Muellner and Roman Gonzenbach and Oli Weinmann and Lisa J Schnell and Thomas Liebscher and Martin E. Schwab},
  journal={The European journal of neuroscience},
  year={2008},
  volume={27 2},
  pages={326-33}
}
Blocking the neurite growth inhibitor Nogo-A by neutralizing antibodies improves functional recovery after partial spinal cord injury. In parallel, regeneration and sprouting of cortico- and rubrospinal projections are increased and may partially explain the enhanced functional recovery. The serotonergic raphe-spinal tract, which plays a key regulatory role for spinal motor circuits, has not been analysed in detail with regard to its response to Nogo-A function blocking antibody treatment after… CONTINUE READING

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Journal Compilation a Federation of European Neuroscience Societies and Blackwell Publishing Ltd

  • A. Müllner
  • The Authors
  • 2008

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