Lamin B1 maintains the functional plasticity of nucleoli.

  title={Lamin B1 maintains the functional plasticity of nucleoli.},
  author={Catherine Martin and Songbi Chen and Apolinar Maya-Mendoza and Josip Lovri{\'c} and P. F. Sims and Dean A Jackson},
  journal={Journal of cell science},
  volume={122 Pt 10},
The dynamic ability of genomes to interact with discrete nuclear compartments appears to be essential for chromatin function. However, the extent to which structural nuclear proteins contribute to this level of organization is largely unresolved. To test the links between structure and function, we evaluated how nuclear lamins contribute to the organization of a major functional compartment, the nucleolus. HeLa cells with compromised expression of the genes encoding lamins were analyzed using… CONTINUE READING
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