Lambda Interferon Restructures the Nasal Microbiome and Increases Susceptibility to Staphylococcus aureus Superinfection.

@article{Planet2016LambdaIR,
  title={Lambda Interferon Restructures the Nasal Microbiome and Increases Susceptibility to Staphylococcus aureus Superinfection.},
  author={Paul J. Planet and Dane Parker and Taylor Sitarik Cohen and Hannah MK Smith and Justinne D Leon and Chanelle L Ryan and Tobin J Hammer and Noah Fierer and Emily I. Chen and Alice Prince},
  journal={mBio},
  year={2016},
  volume={7 1},
  pages={e01939-15}
}
UNLABELLED Much of the morbidity and mortality associated with influenza virus respiratory infection is due to bacterial coinfection with pathogens that colonize the upper respiratory tract such as methicillin-resistant Staphylococcus aureus (MRSA) and Streptococcus pneumoniae. A major component of the immune response to influenza virus is the production of type I and III interferons. Here we show that the immune response to infection with influenza virus causes an increase and restructuring of… CONTINUE READING
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