Lamarckian viral defense in worms

  title={Lamarckian viral defense in worms},
  author={Wayne Peng},
  journal={Nature Genetics},
Numerous studies have highlighted the existence of two distinct stem cell populations in the mouse intestine, one located at the crypt base and marked by expression of Lgr5 and another located at the +4 position relative to the crypt base and marked by expression of Bmi1. Jonathan Epstein and colleagues now show that these two stem cell populations share a bidirectional lineage relationship (Science, published online 10 November 2011; doi:10.1126/science.1213214). The authors identified the… Expand


RNAi promotes heterochromatic silencing through replication-coupled release of RNA polII
It is shown that the alternating arrangement of origins of replication and non-coding RNA in pericentromeric heterochromatin results in competition between transcription and replication in Schizosaccharomyces pombe. Expand