Laetrile: A lesson in cancer quackery

@article{Lerner1981LaetrileAL,
  title={Laetrile: A lesson in cancer quackery},
  author={I J Lerner},
  journal={CA: A Cancer Journal for Clinicians},
  year={1981},
  volume={31}
}
  • I. Lerner
  • Published 1 March 1981
  • Medicine
  • CA: A Cancer Journal for Clinicians
The potential therapeutic effect of Amygdalin (B17), Cobalamin (B12), and Cucurbitapepo (pumpkin seed) extract on Blastocystis in the murine model.
Background:The pathological role of Blastocystis sp. is very controversial which has led to debates on the treatment of this organism, apart from the absence of established diagnostic criteria.
Cyanide Poisoning—“I’m Mr. Blue…”
TLDR
The treatment is supportive care while trying to remove the cyanide from the electron transport chain and reverse its devastating effects.
HORTICULTURE : POST HARVEST TECHNOLOGY Red Wine : Its Importance and Uses
TLDR
Genome or gene editing includes several new techniques such as mega-nucleases, zinc finger nucleases, ZFNs, transcriptional activator-like effector nucleases and the CRISPR/Cas nuclease system to help scientists precisely modify genome sequences.
Synergistic and protective effect of atorvastatin and amygdalin against histopathological and biochemical alterations in Sprague-Dawley rats with experimental endometriosis
TLDR
It is suggested that combined treatment consisting of atorvastatin and amygdalin attenuates endometriosis.
POTENTIAL BENEFITS AND CONTROVERSIES RELATED TO USE OF AMYGDALIN ( VITAMIN B 17 )
TLDR
Vitamin B17 is safe for human consumption, but the bottom line is that more research needs to be done to determine safety for both shortand long-term periods of supplementation.
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References

SHOWING 1-5 OF 5 REFERENCES
Laetrile intoxication. Report of a fatal case.
Laetrile toxicity studies in dogs.
TLDR
These studies demonstrate that oral laetrile is highly toxic when taken with some common table foods and predict that there will be an increased incidence of cyanide poisoning in man as laetile becomes more readily available.
Special report on Laetrile: the NCI Laetrile Review. Results of the National Cancer Institute's retrospective Laetrile analysis.
TLDR
A retrospective analysis of Laetrile treatment undertook in response to widespread public interest allowed no definite conclusions supporting the anti-cancer activity of Laetsrile.
The current status of laetrile.
TLDR
Acceptable clinical studies in humans are lacking, but such ventures would appear to be contraindicated from animal studies and observed human toxicities, and current legal-judicial aspects of laetrile therapy for cancer are discussed.