Laetiporic acids, a family of non-carotenoid polyene pigments from fruit-bodies and liquid cultures of Laetiporus sulphureus (Polyporales, Fungi).

@article{Davoli2005LaetiporicAA,
  title={Laetiporic acids, a family of non-carotenoid polyene pigments from fruit-bodies and liquid cultures of Laetiporus sulphureus (Polyporales, Fungi).},
  author={Paolo Davoli and Adele Mucci and Luisa Schenetti and Roland W. S. Weber},
  journal={Phytochemistry},
  year={2005},
  volume={66 7},
  pages={
          817-23
        }
}
The Laetiporus polyketide synthase LpaA produces a series of antifungal polyenes
TLDR
The identification of an eight-domain mono-modular highly reducing polyketide synthase as sole enzyme necessary for laetiporic acid biosynthesis is described, which underscores the diversity-oriented character of basidiomycete natural product biosynthesis.
Injury-induced biosynthesis of methyl-branched polyene pigments in a white-rotting basidiomycete.
TLDR
A stereaceous basidiomycete was investigated with regard to its capacity to produce yellow pigments after physical injury of the mycelium and demonstrated a polyketide backbone and that the introduction of the sole methyl branch is most likely S-adenosyl-l-methionine-dependent.
Lipid and fatty acid profile of the edible fungus Laetiporus sulphurous. Antifungal and antibacterial properties
TLDR
Results indicated that hexane extracts possessed better antifungal and slightly better antibacterial activity compared to chloroform extracts though both were less active than the commercial antimicrobial agents.
Comparative Studies on the Induction of Trichoderma harzianum Mutanase by α-(1→3)-Glucan-Rich Fruiting Bodies and Mycelia of Laetiporus sulphureus
TLDR
It was shown that the cell wall preparation (CWP) obtained from the fruiting body or vegetative mycelium of polypore fungus Laetiporus sulphureus is rich in α-(1→3)-glucan and can be successfully used for mutanase induction in Trichoderma harzianum.
Production of extracellular polysaccharides by submerged mycelial culture of Laetiporus sulphureus var. miniatus and their insulinotropic properties
TLDR
The EPS were proved to be glucose-rich polysaccharides and were able to increase proliferation and insulin secretary function of rat insulinoma RINm5F cells, in a dose-dependent manner, and strikingly reduced the streptozotocin-induced apoptosis in Rinm5f cells indicating the mode of the cytoprotective role of EPS on RIN m5F Cells.
Production of natural colorants by liquid fermentation with Chlorociboria aeruginascens and Laetiporus sulphureus and prospective applications
TLDR
This study was able to scale up the production of xylindein by Chlorociboria aeruginascens from 3 to 70 L bioreactor cultivations and described for the first time the use of this pigment in silk dyeing, which results in a brilliant hue that cannot be produced by other natural pigments.
Induced Chemical Defense of a Mushroom by a Double-Bond-Shifting Polyene Synthase.
TLDR
This study represents the first characterization of a reducing polyketide synthase from a mushroom and shows that injury-induced de novo synthesis of polyketides is a fungal response strategy.
Multi-omics analysis provides insights into lignocellulosic biomass degradation by Laetiporus sulphureus ATCC 52600
TLDR
The singularity of L. sulphureus ATCC 52600 is shown compared to other Polyporales brown rots, regarding the presence of cellobiohydrolase and peroxidase class II, and the oxidative–hydrolytic metabolism involved in lignocellulose deconstruction is reinforced.
In vitro cultivation of Laetiporus sulphureus and evaluation of its antimicrobial properties.
TLDR
The results shown that the types of culture media for biomass production of L. sulphureus and their aqueous and alcoholic extracts tested against these pathogens have different effects on inhibitory activity.
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