Lactose protects against estrogen-induced pigment gallstones in hamsters fed nutritionally adequate purified diets.

@article{Hayes1989LactosePA,
  title={Lactose protects against estrogen-induced pigment gallstones in hamsters fed nutritionally adequate purified diets.},
  author={K. C. Hayes and Zouhair F. Stephan and Andrzej Pronczuk and Saralyn Lindsey and C Verdon},
  journal={The Journal of nutrition},
  year={1989},
  volume={119 11},
  pages={1726-36}
}
To evaluate the impact of dietary factors on gallstone induction in hamsters, male Syrian hamsters were fed for 2-8 wk purified diets that varied in type and amount of simple sugar (glucose vs. lactose, 17.5-72%), fat (2-5%), fiber (0-15%) and estrogen (0 or 300 micrograms/kg diet). Plasma and liver cholesterol and plasma triglycerides were measured, daily weight gain was determined, cecal weights were obtained, and gallbladder bile was scored by light microscopy and analyzed chemically for its… CONTINUE READING