Lactose digestion and the evolutionary genetics of lactase persistence

@article{Ingram2008LactoseDA,
  title={Lactose digestion and the evolutionary genetics of lactase persistence},
  author={C. Ingram and C. Mulcare and Y. Itan and Mark George Thomas and D. Swallow},
  journal={Human Genetics},
  year={2008},
  volume={124},
  pages={579-591}
}
  • C. Ingram, C. Mulcare, +2 authors D. Swallow
  • Published 2008
  • Biology, Medicine
  • Human Genetics
  • It has been known for some 40 years that lactase production persists into adult life in some people but not in others. However, the mechanism and evolutionary significance of this variation have proved more elusive, and continue to excite the interest of investigators from different disciplines. This genetically determined trait differs in frequency worldwide and is due to cis-acting polymorphism of regulation of lactase gene expression. A single nucleotide polymorphism located 13.9 kb upstream… CONTINUE READING
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