Lactose Contaminant as Steroid Degradation Enhancer

Abstract

By pharmaceutical processes and in the presence of solid excipients physical–chemical changes are known to occur, leading to increased rate of chemical degradation. The purpose of this work was to determine the critical aspects in the stability of a steroid in the presence of a commonly used excipient, lactose. A steroid was either mixed or wet granulated… (More)
DOI: 10.1007/s11095-008-9687-z

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