Lactopeptides and human blood pressure.

  title={Lactopeptides and human blood pressure.},
  author={Johanna M Geleijnse and Mari{\"e}lle F. Engberink},
  journal={Current opinion in lipidology},
  volume={21 1},
PURPOSE OF REVIEW Since the mid-1990s, a number of randomized controlled trials have been published that showed an antihypertensive effect of peptides derived from milk. Research has mainly focused on isoleucine-proline-proline and valine-proline-proline (IPP + VPP), two lactotripeptides that can inhibit the angiotensin-converting enzyme (ACE) in vitro. In Finnish and Japanese subjects with (mild) hypertension, systolic blood pressure (SBP) reductions of approximately 5 mmHg were reported… CONTINUE READING
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