Lactonase activity and status of paraoxonase 1 in Chinese women with polycystic ovarian syndrome.

@article{Zhang2015LactonaseAA,
  title={Lactonase activity and status of paraoxonase 1 in Chinese women with polycystic ovarian syndrome.},
  author={Yujin Zhang and Hongwei Liu and J. He and Kelei Xu and Huai Bai and Ying Wang and Feng Zhang and Jinxia Zhang and Li Min Cheng and Ping Fan},
  journal={European journal of endocrinology},
  year={2015},
  volume={172 4},
  pages={391-402}
}
OBJECTIVE To study the relationship between the lactonase activities and status of paraoxonase 1 (PON1) and its association with the PON1 genetic polymorphisms in women with polycystic ovarian syndrome (PCOS). DESIGN A case-control study. METHODS A total of 455 PCOS patients and 441 control women were included in this study. The lactonase activities and concentrations of PON1 were assayed using 5-thiobutyl butyrolactone (TBBL) and 7-O-diethylphosphoryl-3-cyano-4-methyl-7-hydroxycoumarin… CONTINUE READING
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