Lactoferrin and host defense.

  title={Lactoferrin and host defense.},
  author={Pauline P. Ward and Sonia Uribe-Luna and Orla M. Conneely},
  journal={Biochemistry and cell biology = Biochimie et biologie cellulaire},
  volume={80 1},
Lactoferrin is a multifunctional member of the transferrin family of nonheme iron-binding glycoproteins. Lactoferrin is found at the mucosal surface where it functions as a prominent component of the first line of host defense against infection and inflammation. The protein is also an abundant component of the specific granules of neutrophils and can be released into the serum upon neutrophil degranulation. While the iron-binding properties were originally believed to be solely responsible for… CONTINUE READING