Lactobacillus strains differentially modulate cytokine production by hPBMC from pollen-allergic patients.

@article{Vissers2011LactobacillusSD,
  title={Lactobacillus strains differentially modulate cytokine production by hPBMC from pollen-allergic patients.},
  author={Yvonne M. Vissers and Johannes Snel and Peter F Zuurendonk and Michiel Kleerebezem and Harry J. Wichers and Huub F J Savelkoul},
  journal={FEMS immunology and medical microbiology},
  year={2011},
  volume={61 1},
  pages={28-40}
}
The objective of this study was to assess the potential immunomodulatory effect of six Lactobacillus strains on human peripheral blood mononuclear cells (hPBMC) isolated from allergic patients. hPBMC from patients allergic to birch pollen or grass pollen were cultured in vitro in the presence or absence of selective bacterial strains. Cultures were left unstimulated or stimulated with αCD3/αCD28 or Bet v 1. After 1, 4 and 8 days, cells and culture supernatants were harvested and the effect on… CONTINUE READING