Lactobacillus saerimneri and Lactobacillus ruminis: novel human-derived probiotic strains with immunomodulatory activities.

@article{Taweechotipatr2009LactobacillusSA,
  title={Lactobacillus saerimneri and Lactobacillus ruminis: novel human-derived probiotic strains with immunomodulatory activities.},
  author={Malai Taweechotipatr and Chandra Iyer and Jennifer K Spinler and James Versalovic and Somying Tumwasorn},
  journal={FEMS microbiology letters},
  year={2009},
  volume={293 1},
  pages={65-72}
}
Human-derived lactobacilli were isolated from fecal samples of healthy volunteers. Forty-six isolates from different volunteers were selected and investigated for their immunomodulatory properties. Conditioned medium from each isolate was assessed for its effect on tumor necrosis factor (TNF) production in lipopolysaccharide-activated THP-1 monocytes. Of 46 Lactobacillus isolates, 12 significantly inhibited TNF production in varying magnitude. Lactobacillus strain TH58 displayed the most potent… CONTINUE READING