Lactobacillus casei reduces the Inflammatory Joint Damage Associated with Collagen-Induced Arthritis (CIA) by Reducing the Pro-Inflammatory Cytokines

@article{Amdekar2010LactobacillusCR,
  title={Lactobacillus casei reduces the Inflammatory Joint Damage Associated with Collagen-Induced Arthritis (CIA) by Reducing the Pro-Inflammatory Cytokines},
  author={Sarika Amdekar and Vinod K. Singh and Rambir Singh and Poonam S Sharma and Poonam Keshav and Avnish Kumar},
  journal={Journal of Clinical Immunology},
  year={2010},
  volume={31},
  pages={147-154}
}
This study evaluated the therapeutic efficacy of Lactobacillus casei in treating rheumatoid arthritis using collagen-induced arthritis (CIA) animal model. Healthy female Wistar rats (weight—180–200 g) were included in this study. Oral administration of L. casei was started on the same day. Indomethacin was used as standard reference drug. Serum level of IL-6, α-TNF, and IL-10 were observed. Four-point arthritis indexes were also assessed at the end of week for 28th day. L. casei-treated rats… CONTINUE READING

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