Lactobacilli as live vaccine delivery vectors: progress and prospects.

  title={Lactobacilli as live vaccine delivery vectors: progress and prospects.},
  author={J. F. M. L. Seegers},
  journal={Trends in biotechnology},
  volume={20 12},
Evidence is accumulating that lactobacilli influence the immune response in a strain-dependent manner. This immunomodulatory capacity is important for the development of the immune response, and also identifies Lactobacillus as a potent oral vaccine carrier. Most of our current knowledge of the use of lactobacilli for vaccination purposes has been obtained with tetanus toxin fragment C (TTFC) as the model antigen. This knowledge, together with our ever-increasing understanding of the immune… CONTINUE READING

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