Lactitol, a second-generation disaccharide for treatment of chronic portal-systemic encephalopathy

@article{Uribe1987LactitolAS,
  title={Lactitol, a second-generation disaccharide for treatment of chronic portal-systemic encephalopathy},
  author={Dr. Misael Uribe and Heloisa Toledo and Franz Perez and MSc Florencia Vargas and Sofia Gil BCHem and Guillermo S Garc{\'i}a-Ramos and G P Ravelli and Luis Guevara},
  journal={Digestive Diseases and Sciences},
  year={1987},
  volume={32},
  pages={1345-1353}
}
A double-blind crossover trial was performed to test the therapeutic usefulness and safety of lactitol, a beta-galactoside sorbitol, against lactose in 18 patients with chronic portal-systemic encephalopathy (PSE). The study included four periods: two for washout and two for lactitol and lactose administration. During washout periods, which lasted two weeks each, patients were stabilized with neomycin plus milk of magnesia. Lactitol and lactose were administered during four weeks each. Ten… CONTINUE READING

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