Lactation-induced reduction in rats' acoustic startle is associated with changes in noradrenergic neurotransmission.

@article{Toufexis1999LactationinducedRI,
  title={Lactation-induced reduction in rats' acoustic startle is associated with changes in noradrenergic neurotransmission.},
  author={Donna J Toufexis and Joseph Rochford and Claire Dominique Walker},
  journal={Behavioral neuroscience},
  year={1999},
  volume={113 1},
  pages={176-84}
}
The acoustic startle response (ASR) with or without fear conditioning was compared between cycling (CYC) and lactating (LACT) female rats. ASR sensitivity to changes in endogenous noradrenergic (NA) release was examined using the alpha-2 NA receptor drugs yohimbine and clonidine. Groups of CYC and LACT females were also tested in the open field. ASR was reduced in all LACT, compared with that in CYC females. Both groups exhibited a robust response to fear conditioning and unpotentiated ASR… CONTINUE READING
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