Lactation alters neuropeptide-Y and proopiomelanocortin gene expression in the arcuate nucleus of the rat.

@article{Smith1993LactationAN,
  title={Lactation alters neuropeptide-Y and proopiomelanocortin gene expression in the arcuate nucleus of the rat.},
  author={Mark Scott Smith},
  journal={Endocrinology},
  year={1993},
  volume={133 3},
  pages={1258-65}
}
To identify possible factors associated with lactation that may be involved in the suppression of GnRH neuronal function, we have examined whether lactation induces changes in arcuate nucleus neuronal function, focusing on changes in neuropeptide-Y (NPY) and POMC neuronal activity. Animals were studied during diestrous day 1 of the estrous cycle or during day 10 postpartum. Lactating animals had their litters adjusted to eight pups on day 2 postpartum. Brain tissue was removed to measure NPY… CONTINUE READING

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