Lactate transport by cardiac sarcolemmal vesicles.

  title={Lactate transport by cardiac sarcolemmal vesicles.},
  author={Terry L. Trosper and Kenneth D. Philipson},
  journal={The American journal of physiology},
  volume={252 5 Pt 1},
L-lactate is taken up by cardiac sarcolemmal vesicles in a process that is saturable with respect to L-lactate, stereospecific, associated specifically with the sarcolemmal membrane, and inhibited by other monocarboxylic acids and by the protein modifiers p-chloromercuriphenyl-sulfonate and N-ethylmaleimide. 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid, an inhibitor of the inorganic anion transporter, is without effect. The L-lactate transport is very sensitive to pH. Uptake is stimulated… CONTINUE READING

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