Lactate stimulation of gonococcal metabolism in media containing glucose: mechanism, impact on pathogenicity, and wider implications for other pathogens.

@article{Smith2001LactateSO,
  title={Lactate stimulation of gonococcal metabolism in media containing glucose: mechanism, impact on pathogenicity, and wider implications for other pathogens.},
  author={Harry Smith and Edwin A Yates and Jeff A. Cole and Nick R. Parsons},
  journal={Infection and immunity},
  year={2001},
  volume={69 11},
  pages={6565-72}
}
Over the past decade, studies of Neisseria gonorrhoeae have shown that in media containing glucose, lactate stimulates metabolism, and this could affect pathogenicity (7, 19). Recently, the probable mechanism of this stimulation has been identified as one that could apply to other pathogens (68). Earlier studies implicated lactate metabolism in the serum resistance of Haemophilus influenzae (30), and during the past year, the use of signature-tagged mutagenesis and an infant rat model… CONTINUE READING
Highly Cited
This paper has 37 citations. REVIEW CITATIONS
17 Citations
67 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 17 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 67 references

Functional characterization of a sialyltransferase deficient mutant of Neisseria gonorrhoeae

  • M. J. Gill, D. P. McQuillen, +6 authors H. Smith
  • Infect. Immun
  • 1996
Highly Influential
4 Excerpts

Similar Papers

Loading similar papers…