Lactate release from isolated rat adipocytes: influence of cell size, glucose concentration, insulin and epinephrine.

  title={Lactate release from isolated rat adipocytes: influence of cell size, glucose concentration, insulin and epinephrine.},
  author={D. L. Crandall and S. Fried and A. Francendese and M. Nickel and M. Digirolamo},
  journal={Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme},
  volume={15 7},
  • D. L. Crandall, S. Fried, +2 authors M. Digirolamo
  • Published 1983
  • Chemistry, Medicine
  • Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme
Release of lactate was studied during in vitro incubations with isolated fat cells. Lactate release increased (approximately 3-fold) with increasing medium glucose concentration (from 3 to 12 mM) in both large and small fat cells. Large fat cells from older, fatter rats, however, released 3-4 times more lactate per cell than small fat cells from young rats when incubated with 3, 6 or 12 mM glucose. Insulin and epinephrine produced a marked stimulation of lactate release in small fat cells, but… Expand
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