Lactate production in the perfused rat liver.

@article{Woods1971LactatePI,
  title={Lactate production in the perfused rat liver.},
  author={Henri Woods and Hans A. Krebs},
  journal={The Biochemical journal},
  year={1971},
  volume={125 1},
  pages={129-39}
}
1. In aerobic conditions the isolated perfused liver from well-fed rats rapidly formed lactate from endogenous glycogen until the lactate concentration in the perfusion medium reached about 2mm (i.e. the concentration of lactate in blood in vivo) and then production ceased. Pyruvate was formed in proportion to the lactate, the [lactate]/[pyruvate] ratio… CONTINUE READING