Lactate metabolism in inactive skeletal muscle during lactacidosis.

  title={Lactate metabolism in inactive skeletal muscle during lactacidosis.},
  author={Eva R. Chin and Michael I Lindinger and George J. F. Heigenhauser},
  journal={The American journal of physiology},
  volume={261 1 Pt 2},
Contributions of carbohydrate and fat metabolism to the removal of a lactate (Lac-) load were quantified in inactive soleus (SL), plantaris (PL), and white gastrocnemius (WG) rat hindlimb muscle. Male Sprague-Dawley rats were perfused for 60 min with normal perfusate (NP, n = 8) or a high-lactate perfusate (LP, n = 8), simulating ionic conditions found in arterial blood and plasma after intense exercise: Lac- = 11.0 mM, K+ = 7.88 mM, and pH = 7.15. Metabolite fluxes across the hindlimb were… CONTINUE READING


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