Lactate is always the end product of glycolysis

  title={Lactate is always the end product of glycolysis},
  author={Matthew J Rogatzki and Brian S. Ferguson and Matthew L. Goodwin and L Bruce Gladden},
  booktitle={Front. Neurosci.},
Through much of the history of metabolism, lactate (La(-)) has been considered merely a dead-end waste product during periods of dysoxia. Congruently, the end product of glycolysis has been viewed dichotomously: pyruvate in the presence of adequate oxygenation, La(-) in the absence of adequate oxygenation. In contrast, given the near-equilibrium nature of the lactate dehydrogenase (LDH) reaction and that LDH has a much higher activity than the putative regulatory enzymes of the glycolytic and… CONTINUE READING
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