Lactate dehydrogenase as a biomarker for early renal damage in patients with sickle cell disease.

@article{Alzahri2015LactateDA,
  title={Lactate dehydrogenase as a biomarker for early renal damage in patients with sickle cell disease.},
  author={Mohammad S Alzahri and S. Mousa and Abdulkareem M Almomen and R. Hasanato and J. Polimeni and M. Racz},
  journal={Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia},
  year={2015},
  volume={26 6},
  pages={
          1161-8
        }
}
  • Mohammad S Alzahri, S. Mousa, +3 authors M. Racz
  • Published 2015
  • Medicine
  • Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia
Among many complications of sickle cell disease, renal failure is the main contributor to early mortality. It is present in up to 21% of patients with sickle cell disease. Although screening for microalbuminuria and proteinuria is the current acceptable practice to detect and follow renal damage in patients with sickle cell disease, there is a crucial need for other, more sensitive biomarkers. This becomes especially true knowing that those biomarkers start to appear only after more than 60% of… Expand
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