Lactate dehydrogenase (LDH) gene duplication during chordate evolution: the cDNA sequence of the LDH of the tunicate Styela plicata.

@article{Stock1997LactateD,
  title={Lactate dehydrogenase (LDH) gene duplication during chordate evolution: the cDNA sequence of the LDH of the tunicate Styela plicata.},
  author={David W. Stock and Joseph M. Quattro and Gregory S. Whitt and Dennis A. Powers},
  journal={Molecular biology and evolution},
  year={1997},
  volume={14 12},
  pages={1273-84}
}
L-Lactate dehydrogenase (L-LDH, E.C. 1.1.1.27) is encoded by two or three loci in all vertebrates examined, with the exception of lampreys, which have a single LDH locus. Biochemical characterizations of LDH proteins have suggested that a gene duplication early in vertebrate evolution gave rise to Ldh-A and Ldh-B and that an additional locus, Ldh-C arose in… CONTINUE READING