Lactate as substrate for mitochondrial respiration in alveolar epithelial type II cells.

@article{Lottes2015LactateAS,
  title={Lactate as substrate for mitochondrial respiration in alveolar epithelial type II cells.},
  author={Robyn G Lottes and Danforth A. Newton and Demetri D. Spyropoulos and John E. Baatz},
  journal={American journal of physiology. Lung cellular and molecular physiology},
  year={2015},
  volume={308 9},
  pages={L953-61}
}
Because of the many energy-demanding functions they perform and their physical location in the lung, alveolar epithelial type II (ATII) cells have a rapid cellular metabolism and the potential to influence substrate availability and bioenergetics both locally in the lung and throughout the body. A thorough understanding of ATII cell metabolic function in the healthy lung is necessary for determining how metabolic changes may contribute to pulmonary disease pathogenesis; however, lung metabolism… CONTINUE READING
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