Lactate as a fuel for mitochondrial respiration.

  title={Lactate as a fuel for mitochondrial respiration.},
  author={Gerrit van Hall},
  journal={Acta physiologica Scandinavica},
  volume={168 4},
Lactate production in skeletal muscle has now been studied for nearly two centuries and still its production and functional role at rest and during muscle contraction is a subject of debate. Historically, skeletal muscle was seen mainly as the site of lactate production during contraction and lactate production associated with a lack of muscle oxygenation and fatigue. Later, it was recognized that skeletal muscle not only plays an important role in lactate production but also in lactate… CONTINUE READING