Lactate administration attenuates cognitive deficits following traumatic brain injury

  title={Lactate administration attenuates cognitive deficits following traumatic brain injury},
  author={Ann C. Rice and Robert Zsoldos and Tao Chen and Margaret S Wilson and Malcolm Ross Bullock},
  journal={Brain Research},
Moderately head injured patients often suffer long term neurological sequelae. There is no therapy for brain trauma and current treatments aim only to minimize secondary damage. These secondary effects are often triggered by the inability to re-establish ionic homeostasis after injury, due to large energy demands. Recent reports have demonstrated that neurons are capable of utilizing lactate as an energy source, thus this report examines the usefulness of lactate administration in the… CONTINUE READING


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