Lactate, 3-hydroxybutyrate, and glucose as substrates for the early postnatal rat brain

@article{Dombrowski1989Lactate3A,
  title={Lactate, 3-hydroxybutyrate, and glucose as substrates for the early postnatal rat brain},
  author={George J. Dombrowski and Kenneth R. Swiatek and Kuen-Lan Chao},
  journal={Neurochemical Research},
  year={1989},
  volume={14},
  pages={667-675}
}
The dependence of cerebral energy metabolism upon glucose, 3-hydroxybutyrate, and lactate as fuel sources during the postnatal period was investigated. The brain of 6 day old suckling pups used very little glucose, but by the 15th postnatal day glucose was the major catabolite. Hydroxybutyrate was not a major brain fuel at either 6 or 15 days of age. Its utilization accounted for only 19% of the brain's total energy needs at 15 days of age, even though blood ketone concentrations are near… CONTINUE READING
Highly Cited
This paper has 34 citations. REVIEW CITATIONS

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 21 extracted citations