Lactase persistence versus lactose intolerance: Is there an intermediate phenotype?

@article{Dzialanski2016LactasePV,
  title={Lactase persistence versus lactose intolerance: Is there an intermediate phenotype?},
  author={Zbigniew Dzialanski and Michael Barany and Peter Engfeldt and Anders Magnuson and Lovisa A. Olsson and Torbj{\"o}rn K. Nilsson},
  journal={Clinical biochemistry},
  year={2016},
  volume={49 3},
  pages={248-52}
}
BACKGROUND According to the prevailing theory about the genetic background to lactose intolerance, there are three genotypes but only two adult physiological phenotypes: lactase persistence in individuals with the CT and TT genotypes and lactase non-persistence in individuals with the CC genotype. However, analysis of lactase activity from intestinal biopsies has revealed three distinct levels of activity, suggesting that an intermediate physiological phenotype may exist. AIM To assess… CONTINUE READING