Lack of tumor promoting activity of capsaicin, a principal pungent ingredient of red pepper, in mouse skin carcinogenesis.

@article{Park1998LackOT,
  title={Lack of tumor promoting activity of capsaicin, a principal pungent ingredient of red pepper, in mouse skin carcinogenesis.},
  author={K K Park and K S Chun and Jong In Yook and Young Joon Surh},
  journal={Anticancer research},
  year={1998},
  volume={18 6A},
  pages={4201-5}
}
Capsaicin (trans-8-methyl-N-vanillyl-6-nonenamide) is the major pungent principle of hot peppers of the genus Capsicum. There have been numerous investigations to evaluate the effects of capsaicin on experimental carcinogenesis and mutagenesis, but the results are discordant. In the present study, we have assessed the tumor promoting potential of capsaicin using a two stage mouse skin carcinogenesis model. Repeated applications of capsaicin (10 mumol) onto the shaven backs of female ICR mice… CONTINUE READING
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