Lack of tolerance to ethanol-induced stimulation of mesolimbic dopamine system.

Abstract

Rats maintained for 10 days on a 10% ethanol solution as the sole source of fluid developed marked tolerance to ethanol-induced loss of righting reflex, but no tolerance to the stimulatory effects on mesolimbic dopaminergic system. An ethanol challenge stimulated both the electrical activity of A10 dopaminergic cells and dopamine output in the ventral… (More)

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@article{Diana1992LackOT, title={Lack of tolerance to ethanol-induced stimulation of mesolimbic dopamine system.}, author={Marco Diana and G. L. Gessa and Zachary Rossetti}, journal={Alcohol and alcoholism}, year={1992}, volume={27 4}, pages={329-33} }