Lack of sustained improvement in adherence or viral load following a directly observed antiretroviral therapy intervention.

@article{Berg2011LackOS,
  title={Lack of sustained improvement in adherence or viral load following a directly observed antiretroviral therapy intervention.},
  author={Karina M. Berg and Alain H. Litwin and Xuan Li and Moonseong Heo and Julia H Arnsten},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={2011},
  volume={53 9},
  pages={936-43}
}
BACKGROUND Methadone clinic-based directly observed antiretroviral therapy (DOT) has been shown to be more efficacious for improving adherence and suppressing human immunodeficiency virus (HIV) load than antiretroviral self-administration. We sought to determine whether the beneficial effects of DOT remain after DOT is discontinued. METHODS We conducted a post-trial cohort study of 65 HIV-infected opioid-dependent adults who had completed a 24-week randomized controlled trial of methadone… CONTINUE READING
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