Lack of sequence diversity in the gene encoding merozoite surface protein 5 of Plasmodium falciparum.

@article{Wu1999LackOS,
  title={Lack of sequence diversity in the gene encoding merozoite surface protein 5 of Plasmodium falciparum.},
  author={Tieqiao Wu and Casilda G. Black and Li-na Wang and Alan R. Hibbs and Ross L Coppel},
  journal={Molecular and biochemical parasitology},
  year={1999},
  volume={103 2},
  pages={243-50}
}
The gene encoding merozoite surface protein 5 (MSP5) of Plasmodium falciparum is situated between the genes encoding MSP2 and MSP4 on chromosome 2. Both MSP4 and MSP5 encode proteins that contain hydrophobic signal and glycosylphosphatidylinositol (GPI) attachment signals and a single epidermal growth factor (EGF)-like domain at their carboxyl termini. The similar gene organization, location and similar structural features of the two genes suggest that they have arisen from a gene duplication… CONTINUE READING

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