Lack of selectin-dependent adhesion in prostate cancer cells expressing sialyl Le(x).

BACKGROUND Recently, it has been reported that upregulation of the oligosaccharide sialyl Le(x) (SLe[x]) in prostate cancer is associated with hormone-resistant, aggressive disease. However, it is not clear that SLe(x) expressed on prostate cancer cells has a biological function related to metastatic potential. METHODS The expression levels of SLe(x… (More)