Lack of reproducibility of a single negative sting challenge response in the assessment of anaphylactic risk in patients with suspected yellow jacket hypersensitivity.

@article{Franken1994LackOR,
  title={Lack of reproducibility of a single negative sting challenge response in the assessment of anaphylactic risk in patients with suspected yellow jacket hypersensitivity.},
  author={H H Franken and A E J Dubois and H J Minkema and Sicco Van der Heide and Jan G R de Monchy},
  journal={The Journal of allergy and clinical immunology},
  year={1994},
  volume={93 2},
  pages={431-6}
}
To investigate the reproducibility of a single negative response to sting challenge with a living insect, we rechallenged a group of 61 patients who showed no clinical response to a first sting challenge. All patients had previously had symptoms suggestive of anaphylaxis after a yellow jacket field sting. Thirteen patients (21%) had anaphylactic responses after the second sting challenge, and six of these patients had severe reactions including symptomatic hypotension requiring administration… CONTINUE READING