Lack of replication of a previously reported association between polymorphism in the 3'UTR of the alpha-synuclein gene and Parkinson's disease in Chinese subjects.

@article{Hu2010LackOR,
  title={Lack of replication of a previously reported association between polymorphism in the 3'UTR of the alpha-synuclein gene and Parkinson's disease in Chinese subjects.},
  author={F Hu and W Hu and Lijun Leo Liu and L Yu and Jing Xi and X He and M-R Zhu and Z-L Liu and Y Xu},
  journal={Neuroscience letters},
  year={2010},
  volume={479 1},
  pages={31-3}
}
Recent studies have implicated polymorphisms in the 3' untranslated region (3'UTR) of the alpha-synuclein (SNCA) gene in the development of Parkinson's disease (PD). Single nucleotide polymorphism (SNP) rs356165 is one of polymorphisms located in the 3'UTR and its association with PD has been reported but remains controversial. Herein, we conducted a case-control study to further evaluate the possible association between SNP rs356165 and PD in Chinese. All subjects (330 PD patients and 300… CONTINUE READING