Lack of protection of pre-immunization with saliva of long-term colonized Phlebotomus papatasi against experimental challenge with Leishmania major and saliva of wild-caught P. papatasi.

@article{Ahmed2010LackOP,
  title={Lack of protection of pre-immunization with saliva of long-term colonized Phlebotomus papatasi against experimental challenge with Leishmania major and saliva of wild-caught P. papatasi.},
  author={Sami Ben Hadj Ahmed and Belhassen Kaabi and Ifhem Chelbi and Mohamed Derbali and Saifedine Cherni and Dhafer Laouini and Elyes Zhioua},
  journal={The American journal of tropical medicine and hygiene},
  year={2010},
  volume={83 3},
  pages={512-4}
}
Immunity to saliva of Phlebotomus papatasi protects against Leishmania major infection as determined by co-inoculation of parasites with salivary gland homogenates (SGHs) of this vector. These results were obtained with long-term colonized female P. papatasi. We investigated the effect of pre-immunization with SGH of long-term colonized P. papatasi against L. major infection co-inoculated with SGH of wild-caught P. papatasi. Our results showed that pre-exposure to SGH of long-term, colonized P… CONTINUE READING

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