Lack of prognostic significance of serum DNA methylation of DAPK, MGMT, and GSTPI in patients with non-small cell lung cancer.

@article{Hoffmann2009LackOP,
  title={Lack of prognostic significance of serum DNA methylation of DAPK, MGMT, and GSTPI in patients with non-small cell lung cancer.},
  author={A C Hoffmann and Jussuf Thomas Kaifi and Daniel Vallboehmer and Emre F. Yekebas and Peter P Grimminger and Jessica M. Leers and Jakob Robert Izbicki and Arnulf H Hoelscher and Paul Magnus Schneider and Ralf Metzger and Jan Brabender},
  journal={Journal of surgical oncology},
  year={2009},
  volume={100 5},
  pages={414-7}
}
BACKGROUND AND OBJECTIVES To further improve the screening, diagnosis and therapy of patients with non-small cell lung cancer (NSCLC) additional diagnostic tools are desperately warranted. Aim of this study was to investigate the potential of the DNA methylation of DAPK, MGMT, and GSTPI in serum of patients with NSCLC as a prognostic molecular marker in this disease. METHODS Seventy-six patients with NSCLC were included in this study. The analysis of DNA methylation in serum of patients was… CONTINUE READING