Lack of pathotype specific gene in human Coxiella burnetii isolates.

  title={Lack of pathotype specific gene in human Coxiella burnetii isolates.},
  author={Andreas Stein and Didier Raoult},
  journal={Microbial pathogenesis},
  volume={15 3},
Human Q fever, due to the obligate intracellular bacterium Coxiella burnetii may be acute or chronic. The acute form is rarely fatal, although the chronic form, mostly represented by chronic Q fever endocarditis, is severe and usually fatal in lack of appropriate treatment. A correlation between the human disease state and plasmid types has been described, and specific DNA sequences unique to each plasmid type and which would code for specific pathotypes have been characterized. Because this… CONTINUE READING

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