Lack of nontargeted effects in murine bone marrow after low-dose in vivo X irradiation.

@article{Zyuzikov2011LackON,
  title={Lack of nontargeted effects in murine bone marrow after low-dose in vivo X irradiation.},
  author={Nikolay A Zyuzikov and Philip J Coates and J Michael Parry and Sally A. Lorimore and Eric G. Wright},
  journal={Radiation research},
  year={2011},
  volume={175 3},
  pages={322-7}
}
Exposure to high doses of ionizing radiation unequivocally produces adverse health effects including malignancy. At low doses the situation is much less clear, because effects are generally too small to be estimated directly by epidemiology, and extrapolation of risk and establishment of international rules and standards rely on the linear no-threshold (LNT) concept. Claims that low doses are more damaging than would be expected from LNT have been made on the basis of in vitro studies of… CONTINUE READING