Lack of neuroprotective effects of simvastatin and minocycline in a model of cervical spinal cord injury.

Abstract

Minocycline, a commonly prescribed tetracycline antibiotic, has shown promise as a potential therapeutic agent in animal models of numerous neurologic disorders such as amyotrophic lateral sclerosis, multiple sclerosis, Parkinson's disease, Huntington's disease, stroke, and spinal cord injury (SCI). Simvastatin is one of many hydroxymethylglutaryl-coenzyme… (More)
DOI: 10.1016/j.expneurol.2010.06.018

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