Lack of mutation in the WAF1/CIP1 gene during bovine leukemia virus-induced leukemogenesis.

Abstract

As a cyclin-dependent kinases (Cdks) inhibitor (CDI), the protein p21WAF1/CIP1 is able to interfere with cell cycle progression. Its expression is upregulated by wild-type p53, and the p21WAF1/CIP1 protein appears to be a potent effector of the p53-dependent cell cycle regulatory pathway. We have previously reported that p53 mutations frequently occur… (More)

Topics

Cite this paper

@article{Dequiedt1997LackOM, title={Lack of mutation in the WAF1/CIP1 gene during bovine leukemia virus-induced leukemogenesis.}, author={Frank Dequiedt and Leo A. J. Willems and Pierre Kerkhofs and Ars{\`e}ne Burny and Richard Kettmann}, journal={Veterinary immunology and immunopathology}, year={1997}, volume={59 3-4}, pages={311-22} }