Lack of linkage disequilibrium between transforming growth factor alpha Taq I polymorphism and cleft lip with or without cleft palate in families from Northeastern Italy.

@article{Scapoli1998LackOL,
  title={Lack of linkage disequilibrium between transforming growth factor alpha Taq I polymorphism and cleft lip with or without cleft palate in families from Northeastern Italy.},
  author={Luca Scapoli and Furio Pezzetti and Francesco Carinci and Marcella Martinelli and Paolo Carinci and Mauro Tognon},
  journal={American journal of medical genetics},
  year={1998},
  volume={75 2},
  pages={203-6}
}
Cleft lip with or without cleft palate (CL +/- P) is the most frequent craniofacial malformation in different human populations and its cause is largely unknown. Several studies based on population associations have suggested that an allele mapping in the transforming growth factor alpha locus could be responsible, as a risk factor, for the development of… CONTINUE READING