Lack of interaction between the peptidomimetic substrates captopril and cephradine.

@article{Foster2009LackOI,
  title={Lack of interaction between the peptidomimetic substrates captopril and cephradine.},
  author={D. J. Foster and Shiyin Yee and Barry E. Bleske and Peggy L. Carver and Michael J. Shea and Sujatha S Menon and Chandrasekharan Ramachandran and Lynda S. Welage and Gordon L Amidon},
  journal={Journal of clinical pharmacology},
  year={2009},
  volume={49 3},
  pages={360-7}
}
Intestinal peptide transporters, including hPEPT1, facilitate the absorption of cephalosporins and angiotensin-converting enzyme inhibitors, and have been investigated as a means to improve oral drug absorption. Renal peptide transporters including hPEPT2, may also facilitate renal reabsorption of such compounds. In vitro and animal studies suggest that co… CONTINUE READING