Lack of influence of glutathione S-transferase gene deletions in sporadic breast cancer in Pakistan.

@article{Nosheen2011LackOI,
  title={Lack of influence of glutathione S-transferase gene deletions in sporadic breast cancer in Pakistan.},
  author={Masood Nosheen and Fraz Arshad Malik and Mahmood Akhtar Kayani},
  journal={Asian Pacific journal of cancer prevention : APJCP},
  year={2011},
  volume={12 7},
  pages={1749-52}
}
Glutathione S-transferases constitute the phase II detoxification enzymes involved in the metabolism and detoxification of a wide range of potential environmental carcinogens. GSTM1 and GSTT1 are polymorphic and their deletions have been found to be associated with breast cancer risk in some of the world populations. The current study was aimed at evaluation of GSTM1 and GSTT1 gene deletions in 150 unrelated breast cancer patients and 150 healthy controls from Pakistani population. Multiplex… CONTINUE READING

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