Lack of induction of micronuclei in human peripheral blood lymphocytes treated with hydroquinone.

  title={Lack of induction of micronuclei in human peripheral blood lymphocytes treated with hydroquinone.},
  author={C L Doepker and Kris Dumont and Joseph O'Donoghue and J. Caroline English},
  volume={15 6},
Hydroquinone (HQ) has been reported to produce chromosomal effects in some in vivo and in vitro animal models. Its potential for inducing similar effects in human lymphocytes is less clear. The purpose of this study was to examine human lymphocytes treated with HQ for the presence of chromosomal anomalies, using an accepted assay for micronuclei. In addition, the stability of HQ in culture medium was determined to verify exposures. Lymphocyte cultures were obtained from eight donors so that… CONTINUE READING
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