Lack of exercise, via hindlimb suspension, impedes endogenous neurogenesis.

  title={Lack of exercise, via hindlimb suspension, impedes endogenous neurogenesis.},
  author={Takao Yasuhara and Kento Hara and Mina Maki and Noriyuki Matsukawa and Hidemi Fujino and Isao Date and Cesario V. Borlongan},
  volume={149 1},
Bedridden patients who receive good physical rehabilitation are able to exhibit clinical improvement. Accumulating evidence demonstrates that exercise increases endogenous neurogenesis and may even protect against central nervous system (CNS) disorders. Here, we explored the effects of lack of exercise on neurogenesis in rats by employing a routine hindlimb suspension (HS) model over a 2-week period, which consists of elevating their tails, thereby raising their hindlimbs above the ground and… CONTINUE READING
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